Aaron Boone’s revamped Game 2 lineup couldn’t cure the Yankees’ ills.

The Astros, buoyed by Alex Bregman’s three-run third inning blast, hung on for a 3-2 victory and sent the Yankees home in a daunting 0-2 hole.

For a second straight night, Yankees batters fell victim to the strikeout, fanning 13 times one night after racking up 17 in the series opener.

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Bombers starter Luis Severino did his part, with Bregman’s dinger the only damage over his 5 1/3 innings. He allowed five hits and walked one, tallying six strikeouts on the night.

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